Quotes of life

"It is good to have an end to journey toward, but it is the journey that matters in the end." - Ursula K. Le Guin

Friday, October 18, 2013

Elimination reaction in a nutshell

Dear Students,

In this three-hour class, I will introduce you to another important reaction: 
Elimination.

In the previous lectures, you have seen alkyl halides undergoing nucleophilic 
substitutions (SN), for example:



The reason is that halogens are very good leaving groups. A nucleophile attacks
 the carbon to which the halogen is attached causing the halogen to leave.


An elimination reaction works quite similarly, like this: 



The halogen leaves but also a hydrogen is taken away. The hydrogen is taken away by a base. The result is the formation of an alkene, or double bond.


You will see more examples like this in my lecture. In this class, you will learn about:
-  the two mechanisms of elimination, E1, and E2
-  Stereochemistry of elimination particularly E2
-  Elimination of cyclic alkyl halides
-  Alcohols and amines can also be made to undergo eliminations


Notes for this lesson are availble for download here:
http://bit.ly/18s3joz

Tutorial questions for this topic are available here:
http://bit.ly/H1iRFH


See you in class.





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