Dear Students,
In this three-hour class, I will introduce you to another important reaction:
Elimination.
In the previous lectures, you have seen alkyl halides undergoing nucleophilic
substitutions (SN), for example:
The reason is that halogens are very good leaving groups. A nucleophile attacks
the carbon to which the halogen is attached causing the halogen to leave.
An elimination reaction works quite similarly, like this:
The halogen leaves but also a hydrogen is taken away. The hydrogen is taken away by a base. The result is the formation of an alkene, or double bond.
You will see more examples like this in my lecture. In this class, you will learn about:
- the two mechanisms of elimination, E1, and E2
- Stereochemistry of elimination particularly E2
- Elimination of cyclic alkyl halides
- Alcohols and amines can also be made to undergo eliminations
Notes for this lesson are availble for download here:
http://bit.ly/18s3joz
Tutorial questions for this topic are available here:
http://bit.ly/H1iRFH
See you in class.
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